The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 03, 2006
Filed:
Apr. 26, 2002
Masatoshi Kiuchi, Tokyo, JP;
Takanobu Kuroita, Katano, JP;
Hideo Tomozane, Tokyo, JP;
Shuuzou Takeda, Tokyo, JP;
Yoshihito Tanaka, Tokyo, JP;
Hidemitsu Higashi, Tokyo, JP;
Shigeki Kuwahara, Tokyo, JP;
Masatoshi Kiuchi, Tokyo, JP;
Takanobu Kuroita, Katano, JP;
Hideo Tomozane, Tokyo, JP;
Shuuzou Takeda, Tokyo, JP;
Yoshihito Tanaka, Tokyo, JP;
Hidemitsu Higashi, Tokyo, JP;
Shigeki Kuwahara, Tokyo, JP;
Mitsubishi Pharma Corporation, Osaka, JP;
Abstract
The object of the present invention is to provide a compound having a treatment effect based on a chemokine inhibitory activity, which is satisfactory as a pharmaceutical product for oral administration. The present inventors have found that the following benzylpiperidine derivative (the formula (1)) has a chemokine inhibitory activity. Further intensive studies have resulted in successful enhancement of the chemokine inhibitory activity and stability in blood of the present compound, as well as the completion of the present invention. wherein each symbol is as defined in the specification.