The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 03, 2006
Filed:
May. 01, 2001
Daniela Barlocco, Milan, IT;
Giorgio Cignarella, Milan, IT;
Giuseppe Giardina, Milan, IT;
Mario Grugni, Milan, IT;
Silvano Ronzoni, Milan, IT;
Daniela Barlocco, Milan, IT;
Giorgio Cignarella, Milan, IT;
Giuseppe Giardina, Milan, IT;
Mario Grugni, Milan, IT;
Silvano Ronzoni, Milan, IT;
GlaxoSmithKline S.p.A., Verona, IT;
Abstract
Compounds of formula (I) or a derivative thereof, wherein; R is Calkyl, Ccycloalkyl, Calkoxy, hydroxy, halo, Calkenyl, Calkynyl, amino, Calkylamino, di(Calkyl)amino, hydroxyCalkyl, CalkoxyCalkyl, aminoCalkyl, (Calkyl)aminoCalkyl, di(Calkyl)aminoCalkyl; Ris hydrogen or R; Ris hydroxy, Calkoxy, amino, Calkylamino, di(Calkyl)amino; Ris hydrogen or Calkyl; Rand Rare each independently selected from the list consisting of perhaloCalkyl, hydrogen, halo, Calkyl, Calkoxy, hydroxy, amino, Calkylamino, di(Calkyl)amino, hydroxyCalkyl, CalkoxyCalkyl, aminoCalkyl, (Calkyl)aminoCalkyl, di(Calkyl)aminoCalkyl, aryl, and COX wherein X may be hydroxy, Calkoxy, Calkyl, amino, Calkylamino, or di(Calkyl)amino; with the proviso that, when Ris hydrogen, then Rand Rare not both hydrogen; and wherein any alkyl group or the alkyl moiety of any group containing such a moiety may be substituted one or more times by halo; are ligands of the ORL-1 receptor and are useful in therapy.