The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 03, 2006
Filed:
Jun. 23, 2004
Carles Farrerons Gallemi, Mataro, ES;
Juan Lorenzo Catena Ruiz, L'Hospitalet de Llobregat, ES;
Anna Fernandez Serrat, Sant Cugat del Valles, ES;
Ignacio José Miquel Bono, L'Hospitalet de Llobregat, ES;
Dolors Balsa Lopez, Badalona, ES;
José Ignacio Bonilla Navarro, Daganzo de Arriba, ES;
Carmen Lagunas Arnal, L'Hospitalet de Llobregat, ES;
Carolina Salcedo Roca, Corbera, ES;
Andrés Fernandez Garcia, Barcelona, ES;
Carles Farrerons Gallemi, Mataro, ES;
Juan Lorenzo Catena Ruiz, L'Hospitalet de Llobregat, ES;
Anna Fernandez Serrat, Sant Cugat del Valles, ES;
Ignacio José Miquel Bono, L'Hospitalet de Llobregat, ES;
Dolors Balsa Lopez, Badalona, ES;
José Ignacio Bonilla Navarro, Daganzo de Arriba, ES;
Carmen Lagunas Arnal, L'Hospitalet de Llobregat, ES;
Carolina Salcedo Roca, Corbera, ES;
Andrés Fernandez Garcia, Barcelona, ES;
Laboratorios S.A.L.V.A.T., S.A., Esplugues de Llobregat, ES;
Abstract
The invention relates to carbamates having general structure (I), wherein: R1, R2 and R3 are H, OH, SH, CN, F, Cl, Br, I, (C–C)-alkylthio, (C–C)-alkoxyl, (C–C)-alkoxyl substituted by one or several F radicals, carbamoylamine, (C–C)alkyl and (C–C)alkyl substituted by one or several F or OH radicals; R4 represents a substituted or non-substituted cycloalkyl or cycloaryl radical (a heteroalkyl radical or not). The amine of the quinuclidine ring can also be forming quaternary ammonium salts or in an oxidized state (N-oxide). Carbamates (I) are antagonists of the Mmuscarinic receptor, and selectively, the Mreceptor. Hence, they can be used in the treatment of urinary incontinence (particularly due to bladder instability), irritable bowel syndrome, diseases of the respiratory tract (particularly chronic obstructive pulmonary disease, chronic bronchitis, asthma, emphysema and rhinitis) and in ophthalmologic operations.