The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 03, 2006
Filed:
Oct. 12, 2001
Malcolm F. G. Stevens, Nottingham, GB;
Lloyd R Kelland, Reigate, GB;
Robert a Heald, Kettering, GB;
Cancer Research Technology Limited, London, GB;
Abstract
The present invention pertains to certain N,N-disubstituted quino[4,3,2-kl]acridinium salts of formula (Q) which inhibit telomerase wherein: p is an integer from 0 to 4; q is an integer from 0 to 3; r is an integer from 0 to 4; each Ris —H or a ring substituent; each Ris —H or a ring substituent; each Ris —H or a ring substituent; Ris a nitrogen substituent; Ris a nitrogen substituent; and, Q is an anion. The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit telomerase, to regulate cell proliferation, and in the treatment of proliferative conditions, such as cancer.