The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 03, 2006

Filed:

Jul. 24, 2002
Applicants:

Christopher H. Fotsch, Thousand Oaks, CA (US);

Premilla Arasasingham, Thousand Oaks, CA (US);

Yunxin BO, Thousand Oaks, CA (US);

Ning Chen, Thousand Oaks, CA (US);

Martin H. Goldberg, Woodland Hills, CA (US);

Nianhe Han, Thousand Oaks, CA (US);

Feng-yin Hsieh, Thousand Oaks, CA (US);

Michael G. Kelly, Thousand Oaks, CA (US);

Qingyian Liu, Camarillo, CA (US);

Mark H. Norman, Thousand Oaks, CA (US);

Duncan M. Smith, Thousand Oaks, CA (US);

Markian Stec, Fillmore, CA (US);

Nuria Tamayo, Newbury Park, CA (US);

Ning Xi, Thousand Oaks, CA (US);

Shimin Xu, Moorpark, CA (US);

Inventors:

Christopher H. Fotsch, Thousand Oaks, CA (US);

Premilla Arasasingham, Thousand Oaks, CA (US);

Yunxin Bo, Thousand Oaks, CA (US);

Ning Chen, Thousand Oaks, CA (US);

Martin H. Goldberg, Woodland Hills, CA (US);

Nianhe Han, Thousand Oaks, CA (US);

Feng-Yin Hsieh, Thousand Oaks, CA (US);

Michael G. Kelly, Thousand Oaks, CA (US);

Qingyian Liu, Camarillo, CA (US);

Mark H. Norman, Thousand Oaks, CA (US);

Duncan M. Smith, Thousand Oaks, CA (US);

Markian Stec, Fillmore, CA (US);

Nuria Tamayo, Newbury Park, CA (US);

Ning Xi, Thousand Oaks, CA (US);

Shimin Xu, Moorpark, CA (US);

Assignee:

Amgen Inc., Thousand Oaks, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/496 (2006.01); C07D 401/12 (2006.01); C07D 403/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

Selected substituted piperazine compounds of Formula Iare effective for prophylaxis and treatment of diseases, such as obesity and the like. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving activation of the melanocortin receptor. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.


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