The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 03, 2006
Filed:
Dec. 25, 2001
Makoto Sunagawa, Itami, JP;
Akira Sasaki, Takarazuka, JP;
Makoto Sunagawa, Itami, JP;
Akira Sasaki, Takarazuka, JP;
Dainippon Sumitomo Pharma Co., Ltd., Osaki, JP;
Abstract
Carbapenem compounds having a substituted phenyl or a substituted thienyl directly attached to the-position of carbapenem nucleus as represented by the formula: wherein Ring E is benzene ring or thiophene ring; Ris optionally OH-substituted Calkyl; Rand Rrepresent each H, optionally substituted lower alkyl, etc.; R is H, or a group which is hydrolyzed in the living body to regenerate a carboxyl group, etc.; X is O or S; and Y represents H, lower alkyl, etc., or pharmaceutically acceptable salts thereof and medicaments containing said compound as the active ingredient. These compounds exhibit an excellent antibacterial activity over a broad range of Gram-positive and Gram-negative bacteria, in particular, penicillin-resistant(PRSP) which has been isolated at an elevated frequency in recent years and thus causes a serious clinical problem, andwhich has acquired resistance against the existing β-lactam antibiotics over a wide scope due to penicillin-binding protein (PBP) mutations such as β-lactamase non-producing ampicillin-resistant (BLNAR)