The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 03, 2006
Filed:
Sep. 29, 2000
Applicants:
Haifeng Chen, Castro Valley, CA (US);
Gary Kurtzman, Bryn Mawr, PA (US);
Inventors:
Haifeng Chen, Castro Valley, CA (US);
Gary Kurtzman, Bryn Mawr, PA (US);
Assignee:
Genovo, Inc., Seattle, WA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P 21/06 (2006.01); C12N 15/63 (2006.01); C12N 15/64 (2006.01); A61K 39/12 (2006.01); A01N 63/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
This invention relates to novel adenoviruses useful in the production of high titers of recombinant adeno-associated virus (rAAV) comprising a foreign DNA insert and methods of making these adenoviruses. The adenovirus comprises the AAV rep gene in which the p5 promoter is replaced by a minimal promoter or by no promoter. The invention also provides methods of producing high levels of rAAV as a substantially homogenous preparation and composition of rAAV.