The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 03, 2006

Filed:

Jun. 27, 2003
Applicants:

Ryoichi Hashida, Tsukuba, JP;

Shinji Kagaya, Tokyo, JP;

Yoshihiro Yayoi, Tokyo, JP;

Yuji Sugita, Tsukuba, JP;

Hirohisa Saito, Tokyo, JP;

Inventors:

Ryoichi Hashida, Tsukuba, JP;

Shinji Kagaya, Tokyo, JP;

Yoshihiro Yayoi, Tokyo, JP;

Yuji Sugita, Tsukuba, JP;

Hirohisa Saito, Tokyo, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); C12N 5/08 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Genes whose expression differ between that in eosinophils collected from atopic dermatitis patients of the exabartation stage and those of the remission stage were searched via a differential display method. As a result, NOR-1 (MINOR) gene was successfully identified whose expression significantly increased in eosinophils of patients in the remission stage, a stage associated with a decrease of eosinophils. The present inventors discovered that the gene can be successfully employed in testing for allergic diseases and screening for candidate compounds for therapeutic agents.


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