The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 03, 2006

Filed:

Sep. 26, 2002
Applicants:

Ling X. Shen, Marlboro, MA (US);

Gregory L. Verdine, Lexington, MA (US);

James P. Basilion, Brookline, MA (US);

Vincent P. Stanton, Jr., Belmont, MA (US);

Inventors:

Ling X. Shen, Marlboro, MA (US);

Gregory L. Verdine, Lexington, MA (US);

James P. Basilion, Brookline, MA (US);

Vincent P. Stanton, Jr., Belmont, MA (US);

Assignee:

Variagenics, Inc., Cambridge, MA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); G01N 33/53 (2006.01); C12P 19/00 (2006.01); C07G 3/00 (2006.01); A61K 31/70 (2006.01);
U.S. Cl.
CPC ...
Abstract

Described are methods for identifying targets in RNA molecules based on differences in RNA secondary structure related to sequence variances between different allelic forms. Also described are methods for identifying or developing small molecules which can be used to modulate a target RNA by creation of protein-small-molecule-RNA complexes, as well as compositions which include such small molecules and methods of using those small molecules and compositions.


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