The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 03, 2006
Filed:
Dec. 28, 2001
Scott Powers, Greenlawn, NY (US);
David Mu, Jericho, NY (US);
Phil Xiang, San Francisco, CA (US);
Yue Peng, South Setauket, NY (US);
Scott Powers, Greenlawn, NY (US);
David Mu, Jericho, NY (US);
Phil Xiang, San Francisco, CA (US);
Yue Peng, South Setauket, NY (US);
Amgen SF, LLC, Thousand Oaks, CA (US);
Abstract
The present invention provides methods, reagents, and kits for diagnosing and treating cancer in a mammal, e.g., a human. This invention is based upon the discovery that Pellino 1 or 2 is overexpressed and/or amplified in cancer. Methods to detect cancer or a propensity to develop cancer, to monitor the efficacy of a cancer treatment, and to treat cancer, by inhibiting the expression and/or activity of Pellino 1 or 2 in a cancer cell are included.