The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 03, 2006
Filed:
Feb. 11, 2000
Holger N. Lode, Berlin, DE;
Ralph A. Reisfeld, La Jolla, CA (US);
David A. Cheresh, Encinitas, CA (US);
Stephen D. Gillies, Carlisle, MA (US);
Holger N. Lode, Berlin, DE;
Ralph A. Reisfeld, La Jolla, CA (US);
David A. Cheresh, Encinitas, CA (US);
Stephen D. Gillies, Carlisle, MA (US);
The Scripps Research Institute, La Jolia, CA (US);
EMD Lexigen Research Center Corp., Billerica, MA (US);
Abstract
The invention teaches methods for treating tumors and tumor metastases in a mammal comprising administering, to a mammal in need of treatment, a therapeutic amount of an antagonist sufficient to inhibit angiogenesis in combination with a therapeutic amount of anti-tumor immunotherapeutic agent, such as a anti-tumor antigen antibody/cytokine fusion protein having a cytokine and a recombinant immunoglobulin polypeptide chain sufficient to elicit a cytokine-specific biological response.