The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 03, 2006
Filed:
Apr. 06, 2000
Weng Tao, Lincoln, RI (US);
David H. Rein, Cambridge, MA (US);
Brenda J. Dean, Cumberland, RI (US);
Paul F. Stabila, Coventry, RI (US);
Moses B. I. Goddard, Tiverton, RI (US);
Weng Tao, Lincoln, RI (US);
David H. Rein, Cambridge, MA (US);
Brenda J. Dean, Cumberland, RI (US);
Paul F. Stabila, Coventry, RI (US);
Moses B. I. Goddard, Tiverton, RI (US);
Neurotech S.A., Evry, FR;
Abstract
ARPE-19 cells were evaluated as a platform cell line for encapsulated and unencapsulated cell-based delivery technology. ARPE-19 cells were found to be hardy (the cell line is viable under stringent conditions, such as in central nervous system or intra-ocular environment); can be genetically modified to secrete the protein of choice; have a long life span; are of human origin; have good in vivo device viability; deliver efficacious quantity of growth factor; trigger no or low level host immune reaction, and are non-tumorigenic.