The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 03, 2006

Filed:

Apr. 09, 1999
Applicants:

Richard C. Allen, Flemington, NJ (US);

Michael Cornfeldt, Morristown, NJ (US);

Inventors:

Richard C. Allen, Flemington, NJ (US);

Michael Cornfeldt, Morristown, NJ (US);

Assignee:

Titan Pharmaceuticals, Inc., Somerville, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 66/00 (2006.01); A01N 65/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides methods for the treatment of abnormal psychiatric states, particularly the negative symptoms of schizophrenia and extrapyramidal side effects (EPS) of antipsychotic drugs. The inventive methods relate to the administration of therapeutic cells (which produce dopamine or dopamine precursors) adhered to support matrices to subjects suffering from the negative symptoms of schizophrenia and/or EPS. The therapeutic cells may be coadministered with cells which protect the therapeutic cells from immune rejection and/or cells which produce neurotrophic factors which improve the viability of the therapeutic cells.


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