The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 26, 2006
Filed:
Oct. 01, 2004
Franz Weiberth, Raritan Township, NJ (US);
George Everett Lee, Somerville, NJ (US);
Reda G. Hanna, Allentown, PA (US);
Juergen Mueller-lehar, Weinolsheim, DE;
Silke Dubberke, Floersheim, DE;
Roland Utz, Kronberg, DE;
Franz Weiberth, Raritan Township, NJ (US);
George Everett Lee, Somerville, NJ (US);
Reda G. Hanna, Allentown, PA (US);
Juergen Mueller-Lehar, Weinolsheim, DE;
Silke Dubberke, Floersheim, DE;
Roland Utz, Kronberg, DE;
Aventis Pharmaceuticals Inc., Bridgewater, NJ (US);
Abstract
An improved process for the preparation of N-amino nitrogen heterocyclic compounds is disclosed and claimed. In an embodiment of this invention, a compound of the formula (VI) is prepared starting from the corresponding indole derivative by way of N-amination and subsequently forming an hydrazone by the reaction with a keto compound in a single step. Further reduction of the hydrazone and subsequent coupling with a pyridine compound affords the compound of formula VI or a suitable salt thereof.