The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 26, 2006

Filed:

Nov. 03, 2003
Applicants:

Bradford Van Wagenen, Salt Lake City, UT (US);

Thomas M. Stormann, Salt Lake City, UT (US);

Scott T Moe, Marlborough, UT (US);

Susan M Sheehan, Dexter, MI (US);

Donald Mcleod, Salt Lake City, UT (US);

Daryl L Smith, Fishers, IN (US);

Methvin Isaac, Toronto, CA;

Abdelmalik Slassi, Toronto, CA;

Ian Egle, Toronto, CA;

Louise Edwards, Toronto, CA;

Tomislav Stefanac, Toronto, CA;

Tao Xin, Toronto, CA;

Jalaj Arora, Toronto, CA;

William Michne, Wilmington, DE (US);

Inventors:

Bradford Van Wagenen, Salt Lake City, UT (US);

Thomas M. Stormann, Salt Lake City, UT (US);

Scott T Moe, Marlborough, UT (US);

Susan M Sheehan, Dexter, MI (US);

Donald McLeod, Salt Lake City, UT (US);

Daryl L Smith, Fishers, IN (US);

Methvin Isaac, Toronto, CA;

Abdelmalik Slassi, Toronto, CA;

Ian Egle, Toronto, CA;

Louise Edwards, Toronto, CA;

Tomislav Stefanac, Toronto, CA;

Tao Xin, Toronto, CA;

Jalaj Arora, Toronto, CA;

William Michne, Wilmington, DE (US);

Assignees:

NPS Pharmaceuticals, Inc., Salt Lake City, UT (US);

Astrazeneca AB, Sodertalje, SE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/44 (2006.01); C07D 401/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides compounds and pharmaceutical compositions that act as antagonists at metabotropic glutamate receptors, and that are useful for treating neurological diseases and disorders. Methods of preparing the compounds also are disclosed.


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