The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 26, 2006
Filed:
Feb. 11, 2000
Amanda J. Patel, Juan les Pins, FR;
Eric Honore, Juan les Pins, FR;
Florian Lesage, Valbonne, FR;
Georges Romey, Nice, FR;
Michel Lazdunski, Nice, FR;
Michel Fink, Bagnols sur Ceze, FR;
Fabrice Duprat, Mougins, FR;
Francois Maingret, Bristol, GB;
Amanda J. Patel, Juan les Pins, FR;
Eric Honore, Juan les Pins, FR;
Florian Lesage, Valbonne, FR;
Georges Romey, Nice, FR;
Michel Lazdunski, Nice, FR;
Michel Fink, Bagnols sur Ceze, FR;
Fabrice Duprat, Mougins, FR;
Francois Maingret, Bristol, GB;
Abstract
Human and mouse TREK-1 potassium transport proteins are disclosed as well a method for using potassium transport proteins for identifying substances having anesthetic properties, such as producing a safe, reversible state of unconsciousness with concurrent amnesia and analgesia in a mammal upon inhalation, in a method comprising (a) contacting the test substance with a mammalian potassium transport protein, wherein said potassium transport protein exhibits outward-going potassium rectification; and (b) determining the potassium transport activity of the potassium transport protein, wherein an activation of potassium transport is indicative of the test substance having anesthetic properties.