The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 19, 2006
Filed:
Feb. 04, 2000
Hermann Kuenzer, Berlin, DE;
Rudolf Knauthe, Berlin, DE;
Monika Lessl, Berlin, DE;
Karl-heinrich Fritzemeier, Berlin, DE;
Christa Hegele-hartung, Muelheim a.d. Ruhr, DE;
Ulf Boemer, Berlin, DE;
Gerd Mueller, Jena, DE;
Dirk Kosemund, Erfurt, DE;
Hermann Kuenzer, Berlin, DE;
Rudolf Knauthe, Berlin, DE;
Monika Lessl, Berlin, DE;
Karl-Heinrich Fritzemeier, Berlin, DE;
Christa Hegele-Hartung, Muelheim a.d. Ruhr, DE;
Ulf Boemer, Berlin, DE;
Gerd Mueller, Jena, DE;
Dirk Kosemund, Erfurt, DE;
Schering AG, Berlin, DE;
Abstract
The invention describes new compounds as pharmaceutical active ingredients, which have in vitro a higher affinity to estrogen receptor preparations from rat prostates than to estrogen receptor preparations from rat uteri and in vivo a preferential action on bone rather than the uterus, their production, their therapeutic use and pharmaceutical dispensing forms that contain the new compounds. The new compounds are 16α- and 16β-hydroxy-estra-1,3,5(10)-estratrienes, which carry additional substituents on the steroid skeleton and can have one or more additional double bonds in the B-, C- and/or D-rings.