The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 19, 2006
Filed:
Mar. 03, 2004
Robert Lum, Palo Alto, CA (US);
Cheri Lynn Blum, Alameda, CA (US);
Richard Mackman, San Bruno, CA (US);
Michael Wick, Portola Valley, CA (US);
Steven Schow, Redwood Ciy, CA (US);
Jeff Zablocki, Mountain View, CA (US);
Prabha Ibrahim, Mountain View, CA (US);
Robert Lum, Palo Alto, CA (US);
Cheri Lynn Blum, Alameda, CA (US);
Richard Mackman, San Bruno, CA (US);
Michael Wick, Portola Valley, CA (US);
Steven Schow, Redwood Ciy, CA (US);
Jeff Zablocki, Mountain View, CA (US);
Prabha Ibrahim, Mountain View, CA (US);
CV Therapeutics, Inc., Palo Alto, CA (US);
Abstract
Compounds of the following formula are provided: In the Formula (I), Ris —X—R'; in which R′ is optionally substituted lower alkyl, optionally substituted aryl, optionally substituted heteroaryl, or optionally substituted heterocyclyl, and X is —NH—. Ris lower alkyl optionally substituted with one, two or three groups chosen from hydroxy, lower alkoxy, and halogen. And Ris —NRR; in which Ris hydrogen and Ris lower alkyl substituted with amino; or (ii) Rand Rare both lower alkyl optionally substituted with one, two or three groups chosen from hydroxy and amino. It is to be understood that R′ is not cyclohexylmethyl, phenyl, substituted phenyl, benzyl, phenylethyl, or m-hydroxybenzyl. The compounds inhibit CDK-2 activity and are useful for treating disorders characterized by undesirable cell proliferation.