The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 19, 2006

Filed:

Aug. 14, 2002
Applicants:

George Kunos, Bethesda, MD (US);

Raj K. Razdan, Gloucester, MA (US);

Inventors:

George Kunos, Bethesda, MD (US);

Raj K. Razdan, Gloucester, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/075 (2006.01); C07C 43/205 (2006.01);
U.S. Cl.
CPC ...
Abstract

Methods and compounds for reversing pathological vasodilation of blood vessels, for example vasodilation caused by activation of CB1-like receptors, by administering to a subject a therapeutically effective amount of a compound sufficient to induce vasoconstriction, the compound comprising: wherein dashed lines independently represent either a single or a double bond, Ris a lower alkyl, Ris a lower alkyl, Ris a lower alkyl or halogen, Ris a lower alkyl or hydrogen, Ris a lower alkyl or hydrogen, Ris a hydrogen, lower alkyl or halogen, and Ris a hydrogen, lower alkyl or halogen. The vasoconstrictor can be used for a variety of purposes, including hemostasis or the treatment of shock, for example vasodilatory shock syndromes such as septic shock.


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