The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 19, 2006

Filed:

Nov. 20, 2002
Applicants:

Philippe Burnier, Maisons-Laffitte, FR;

Jacques Froissant, Brevainville, FR;

Benoît Marabout, Massy, FR;

Frank Marguet, Verrieres le Buisson, FR;

Frédéric Puech, La Celle Saint Cloud, FR;

Inventors:

Philippe Burnier, Maisons-Laffitte, FR;

Jacques Froissant, Brevainville, FR;

Benoît Marabout, Massy, FR;

Frank Marguet, Verrieres le Buisson, FR;

Frédéric Puech, La Celle Saint Cloud, FR;

Assignee:

Sanofi-Aventis, Paris, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61K 31/5025 (2006.01); C07D 209/04 (2006.01); A61P 25/22 (2006.01); A61P 25/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention concerns compounds of general formula (I), wherein: X represents a hydrogen or halogen atom; Rrepresents a hydrogen atom or a (C–C)alkyl group; Rand R, represent each, independently of each other, a hydrogen atom or a (C–C)alkyl group, or Rand Rform, with the atom which bears them, a pyrrolidinyl, piperidinyl, morpholinyl or 4-alkylpiperazinyl group; and Het represents a heteroaromatic group of pyridinyl, 1-oxidopyridinyl, quinolinyl, isoquinolinyl, pyrimidinyl, pyrazinyl, pyridazinyl type, the heteroaromatic group may represent one or several halogen atoms and/or one or several (C–C)alkyl, (C–C)alkoxyl groups; in the form of bases, addition salts to acids, solvates or hydrates. The invention also concerns pharmaceutical compositions containing same, methods for preparing same and synthesis intermediates


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