The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7109015 B1

PDF
Full Text
Expired
Date of Patent:
Sep. 19, 2006

Filed:

Mar. 29, 2004
Applicant:

You-di Liao, Taipei, TW;

Inventor:

You-Di Liao, Taipei, TW;

Assignee:

Academia Sinica, Taipei, TW;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 9/52 (2006.01); C12N 15/57 (2006.01); C12N 15/70 (2006.01); C12P 21/06 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides methionine aminopeptidases (MetAPs) with a broad substrate range, particularly those capable of removing the N-terminal Met from bulky or acidic penultimate residues. In preferred embodiments, these MetAPs have mutations at the 233, 206 and/or 168 positions of SEQ ID NO:1. Preferably, amino acids at these residues are substituted with glycine or threonine. Also provided are cells comprising the MetAPs, DNA encoding the MetAPs, and methods of using the MetAPs.


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Liao, You-Di. (2006). Removal of n-terminal methionine from proteins by engineered methionine aminopeptidase (U.S. Patent No. 7109015). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7109015

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