The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 12, 2006
Filed:
Jun. 18, 2004
Mingqi Zhao, San Jose, CA (US);
Iuliu Blaga, Fremont, CA (US);
Luc Bousse, Los Altos, CA (US);
John Stults, Redwood City, CA (US);
Jing NI, Sunnyvale, CA (US);
Mingqi Zhao, San Jose, CA (US);
Iuliu Blaga, Fremont, CA (US);
Luc Bousse, Los Altos, CA (US);
John Stults, Redwood City, CA (US);
Jing Ni, Sunnyvale, CA (US);
Predicant Biosciences, Inc., South San Francisco, CA (US);
Abstract
A microfluidic chip formed with multiple fluid channels terminating at a tapered electrospray ionization tip for mass spectrometric analysis. The fluid channels may be formed onto a channel plate that are in fluid communication with corresponding reservoirs. The electrospray tip can be formed along a defined distal portion of the channel plate that can include a single or multiple tapered surfaces. The fluid channels may terminate at an open-tip region of the electrospray tip. A covering plate may substantially enclose most portions of the fluid channels formed on the channel plate except for the open-tip region. Another aspect of the invention provides methods for conducting mass spectrometric analysis of multiple samples flowing through individual fluid channels in a single microfluidic chip that is formed with a tapered electrospray tip having an open-tip region.