The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 12, 2006
Filed:
Oct. 01, 2003
Ramesh Dandala, Hyderabad, IN;
V. V. Prasada Rao Korrapati, Hyderabad, IN;
Meenakhshisunderam Sivakumaran, Hyderabad, IN;
Ramesh Dandala, Hyderabad, IN;
V. V. Prasada Rao Korrapati, Hyderabad, IN;
Meenakhshisunderam Sivakumaran, Hyderabad, IN;
Aurobind - Pharma Ltd., Hyderabad, IN;
Abstract
The present invention relates to a novel process for the preparation of a cefdinir by reacting O-acetyl thioester of Formula I with in the presence of a base in suitable solvent wherein R' represents H or any carboxyl protecting group, and then converting to the cefdinir by the removal of protecting groups. This invention also relates to making the cefdinir using a novel process to prepare the O-acetyl thioester intermediate (Formula I) by condensing (Z)-2-(2-amino-4-thiazolyl)-2-acetyloxyiminoacetic acid with bis(benzothiazol-2-yl)disulphide in the presence of triphenylphosphine and a base in a suitable solvent.