The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 12, 2006

Filed:

Sep. 06, 2002
Applicants:

James L. Yeager, Lake Forest, IL (US);

Nadir Büyüktimkin, Robbinsville, NJ (US);

Servet Büyüktimkin, Robbinsville, NJ (US);

Inventors:

James L. Yeager, Lake Forest, IL (US);

Nadir Büyüktimkin, Robbinsville, NJ (US);

Servet Büyüktimkin, Robbinsville, NJ (US);

Assignee:

NexMed Holdings, Inc., East Windsor, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/5575 (2006.01); A61K 47/36 (2006.01); A61K 31/736 (2006.01); A61K 9/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides methods and compositions for treating erectile dysfunction. The methods include the step of placing within the fossa navicularis of the patient an effective erection-inducing amount of a vasoactive prostaglandin composition of a semi-solid consistency. The composition comprises a vasoactive prostaglandin, a penetration enhancer, a shear-thinning polysaccharide, a lipophilic compound, and an acidic buffer system. The penetration enhancer is an alkyl-2-(N-substituted amino)-alkanoate ester, a (N-substituted amino)-alkanol alkanoate, or a mixture of these enhancers. The lipophilic compound may be an aliphatic Cto Calcohol, aliphatic Cto Cester, an aliphatic Cto Cester, or a mixture of these. The composition includes a buffer system providing a buffered pH value for said composition in the range of about 3 to about 7.4.


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