The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 12, 2006
Filed:
Mar. 02, 2000
Tsunetoshi Honma, Osaka, JP;
Yoshiharu Hiramatsu, Osaka, JP;
Akinori Arimura, Toyonaka, JP;
Shionogi & Co., Ltd., Osaka, JP;
Abstract
The present invention provides novel compounds having a dual antagonistic activity against thromboxane A2 receptor and prostaglandin Dreceptor and pharmaceutical compositions comprising them. A compound of the formula (I): wherein Ris —CH—CH═CH—CH—CH—CH—COORor —CH═CH—CH—CH—CH—COOR; Ris hydrogen or alkyl; m is 0 or 1; p is 0 or 1; Xand Xeach is independently optionally substituted aryl or optionally substituted heteroaryl; Xis a bond, —CH—, —S—, —SO—, —CH—O—, —O—CH—, —CH—S—, —S—CH—, or the like; Xis —CH—, —CH—CH—, —C(═O)—, or the like, have a dual antagonistic activity against both a thromboxane Areceptor and a prostaglandin Dreceptor.