The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 12, 2006

Filed:

Feb. 20, 2001
Applicants:

Christopher Love, Janssen Pharmaceutica N.V., Turnhoutseweg 30, Beerse, 2340, BE;

Jean Pierre Frans Van Wauwe, Janssen Pharmaceutica N.V., Tumhoutseweg 30, Beerse, 2340, BE;

Marc DE Brabander, Janssen Pharmaceutica N.V., Tumhoutseweg 30, Beerse, 2340, BE;

Ludwig Cooymans, Janssen Pharmaceutica N.V., Tumhoutseweg 30, Beerse, 2340, BE;

Nele Vandermaesen, Janssen Pharmaceutica N.V., Tumhoutseweg 30, Beerse, 2340, BE;

Ludo Edmond Josephine Kennis, Janssen Pharmaceutica N.V., Tumhoutseweg 30, Beerse, 2340, BE;

Inventors:

Christopher Love, Janssen Pharmaceutica N.V., Turnhoutseweg 30, Beerse, 2340, BE;

Jean Pierre Frans Van Wauwe, Janssen Pharmaceutica N.V., Tumhoutseweg 30, Beerse, 2340, BE;

Marc De Brabander, Janssen Pharmaceutica N.V., Tumhoutseweg 30, Beerse, 2340, BE;

Ludwig Cooymans, Janssen Pharmaceutica N.V., Tumhoutseweg 30, Beerse, 2340, BE;

Nele Vandermaesen, Janssen Pharmaceutica N.V., Tumhoutseweg 30, Beerse, 2340, BE;

Ludo Edmond Josephine Kennis, Janssen Pharmaceutica N.V., Tumhoutseweg 30, Beerse, 2340, BE;

Assignee:

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/41 (2006.01); A61K 31/425 (2006.01); A61K 31/415 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention concerns the use of a compound of formula (I') a N-oxide, pharmaceutically acceptable addition salt, quaternary amine and stereochemically isomeric form thereof, wherein Q is optionally substituted Ccycloalkyl, phenyl, naphthyl, pyridyl, pyrimidinyl, pyrazinyl, pyridazinyl, benzthiazolyl, benzoxazolyl, benzimidazolyl, indazolyl, or imidazopyridyl; or Q is a radical of formula wherein X and Y each independently are O, NR, CHor S, with Rbeing hydrogen or Calkyl; q is 1 to 4; Z is O or NRwith Rbeing hydrogen or Calkyl; r is 1 to 3; L is optionally substituted phenyl or L is Het with Het being an optionally substituted five- or six-membered heterocyclic ring or an optionally substituted bicyclic heterocyclic ring; for the manufacture of a medicament for the prevention or the treatment of diseases mediated through cytokines.


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