The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 12, 2006
Filed:
Dec. 03, 2003
Denis Gravel, St-Lambert, CA;
Elaref S. Ratemi, St-Laurent, CA;
Mostafa Hatam, Brossard, CA;
Guy Boileau, Brossard, CA;
Philippe Crine, Outremont, CA;
Isabelle Lemire, Montreal, CA;
Denis Gravel, St-Lambert, CA;
Elaref S. Ratemi, St-Laurent, CA;
Mostafa Hatam, Brossard, CA;
Guy Boileau, Brossard, CA;
Philippe Crine, Outremont, CA;
Isabelle Lemire, Montreal, CA;
Enobia Pharma, Montreal, CA;
Abstract
The present invention relates to derivatives of succinic and glutaric acids and analogues thereof, having the following general formula: useful as inhibitors of PHEX. These derivatives are useful for promoting generation of bone mass and treating or preventing diseases or conditions associated with a phosphate metabolism defect. Methods for preparation and intermediates are also disclosed.