The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 12, 2006
Filed:
May. 21, 2001
Jose Luis Castro Pineiro, Bishop's Stortford, GB;
Ian Churcher, Great Dunmow, GB;
Alexander Richard Guiblin, Cambourne, GB;
Timothy Harrison, Great Dunmow, GB;
Sonia Kerrard, Harlow, GB;
Andrew Madin, Sawbridgeworth, GB;
Alan John Nadin, Sawbridgeworth, GB;
Andrew Pate Owens, Huntingdon, GB;
Timothy Jason Sparey, London, GB;
Martin Richard Teall, Bishop's Stortford, GB;
Susannah Williams, Harlow, GB;
Jose Luis Castro Pineiro, Bishop's Stortford, GB;
Ian Churcher, Great Dunmow, GB;
Alexander Richard Guiblin, Cambourne, GB;
Timothy Harrison, Great Dunmow, GB;
Sonia Kerrard, Harlow, GB;
Andrew Madin, Sawbridgeworth, GB;
Alan John Nadin, Sawbridgeworth, GB;
Andrew Pate Owens, Huntingdon, GB;
Timothy Jason Sparey, London, GB;
Martin Richard Teall, Bishop's Stortford, GB;
Susannah Williams, Harlow, GB;
Merck Sharp & Dohme Limited, Hoddesdon, GB;
Abstract
A novel class of 1,4- and 1,5-benzodiazepines of formula (I) is disclosed. The compounds modulate the processing of amyloid precursor protein by γ-secretase, and hence find use in the treatment or prevention of conditions associated with the deposition of β-amyloid, such as Alzheimer's disease