The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 12, 2006

Filed:

Feb. 15, 2002
Applicants:

Zaihui Zhang, Richmond, CA;

Timothy S. Daynard, Vancouver, CA;

Serguei V. Sviridov, Burnaby, CA;

Mikhail A. Chafeev, Vancouver, CA;

Shisen Wang, Coquitlam, CA;

Inventors:

Zaihui Zhang, Richmond, CA;

Timothy S. Daynard, Vancouver, CA;

Serguei V. Sviridov, Burnaby, CA;

Mikhail A. Chafeev, Vancouver, CA;

Shisen Wang, Coquitlam, CA;

Assignee:

QLT Inc., Vancouver, CA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/655 (2006.01); A61K 31/415 (2006.01); C07D 231/38 (2006.01);
U.S. Cl.
CPC ...
Abstract

Pharmaceutical compositions and compounds are provided. The compounds of the invention demonstrate anti-proliferative activity, and may promote apoptosis in cells lacking normal regulation of cell cycle and death. In one embodiment of the invention, pharmaceutical compositions of the compounds in combination with a physiologically acceptable carrier are provided. The pharmaceutical compositions are useful in the treatment of hyperproliferative disorders, which disorders include tumor growth, lymphoproliferative diseases, angiogenesis. The compounds of the invention are substituted pyrazoles and pyrazolines.


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