The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 12, 2006

Filed:

Sep. 16, 2005
Applicant:

Ichiro Yamashita, Nara, JP;

Inventor:

Ichiro Yamashita, Nara, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P 9/00 (2006.01); G01N 33/543 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to a precious metal-recombinant apoferritin complex produced by recombination technique, wherein the precious metal is gold (Au) or platinum (Pt), and wherein the residues of glutamic acid and aspartic acid in a channel of apoferritin complex are substituted with small polar amino acid residues or/and noncharged amino acid residues, e.g., serine, or/and with basic amino acid residues, e.g., lysine. The substitution prevents a repulsive force due to electrostatic interaction between a metal ion, e.g., (AuCl)that has a negative charge and a negative amino acid residue of the apoferritin, and facilitates the capture of (AuCl)into holding portion in the channel of said metal-recombinant apoferritin complex. The captured (AuCl)is subsequently reduced to Au, and thus the gold-recombinant apoferritin complex is produced.


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