The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7105317 B1

PDF
Full Text
Expired
Date of Patent:
Sep. 12, 2006

Filed:

Mar. 10, 2003
Applicants:

Pascale Gueirard, Meudon la Foret, FR;

Nicole Guiso, Paris, FR;

Inventors:

Pascale Gueirard, Meudon la Foret, FR;

Nicole Guiso, Paris, FR;

Assignee:

Institut Pasteur, Paris, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/04 (2006.01); A01N 63/00 (2006.01); A61K 39/10 (2006.01); A61K 45/00 (2006.01); C12M 1/00 (2006.01); C12M 3/00 (2006.01); C12N 1/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention relates to an immunogenic composition comprising a bacterial extract containing at least one expression products of the vrg genes of a strain ofchosen from, or. The invention also relates to a method for producing the extract, comprising culturing the bacteria on blood medium to obtain isolated nonhemolytic colonies; inoculating cells of one or more colonies in liquid medium to give a suspension of cells; separating the cells from the liquid medium after culture; suspending the separated cells in a buffer comprising urea for at least an amount of time sufficient to form a bacterial lysate; and separating intact cells and insoluble material from soluble material, wherein the extract comprises the soluble material.


Find Patent Forward Citations

Loading…