The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 12, 2006
Filed:
Sep. 09, 2002
Applicants:
Charles J. Arntzen, Ithaca, NY (US);
Mary E. Blake, Tucson, AZ (US);
Jordan U. Gutterman, Houston, TX (US);
Inventors:
Charles J. Arntzen, Ithaca, NY (US);
Mary E. Blake, Tucson, AZ (US);
Jordan U. Gutterman, Houston, TX (US);
Assignee:
Research Development Foundation, Carson City, NV (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/78 (2006.01); C12N 5/10 (2006.01); C12N 5/00 (2006.01); C12P 19/44 (2006.01); A01N 43/04 (2006.01);
U.S. Cl.
CPC ...
Abstract
The invention provides saponin mixtures and compounds which are isolated from the speciesand methods for their use. These compounds may contain a triterpene moiety, such as acacic or oleanolic acid, to which oligosaccharides and monoterpenoid moieties are attached. The mixtures and compounds have properties related to the regulation of apoptosis and cytotoxicity of cells and exhibit potent anti-tumor effects against a variety of tumor cells.