The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 12, 2006

Filed:

Jan. 07, 2002
Applicants:

Frederick D. Quinn, Avondale Estates, GA (US);

Kristin A. Birkness, Atlanta, GA (US);

Manon Deslauriers, Quebec City, CA;

Peter King, Nacogdoches, TX (US);

David S. Beall, Atlantic Beach, FL (US);

Inventors:

Frederick D. Quinn, Avondale Estates, GA (US);

Kristin A. Birkness, Atlanta, GA (US);

Manon Deslauriers, Quebec City, CA;

Peter King, Nacogdoches, TX (US);

David S. Beall, Atlantic Beach, FL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/04 (2006.01); A61K 49/00 (2006.01); A61K 39/395 (2006.01); C12Q 1/00 (2006.01); C12N 5/00 (2006.01); C12N 5/08 (2006.01);
U.S. Cl.
CPC ...
Abstract

Provided herein is an in vitro granuloma model and methods of its use. Methods of detecting and/or diagnosing latent tuberculosis in a subject are also provided, as are latency-specific antigens (and antibodies thereto), such as α-crystallin, and methods of identifying and using such molecules. Also provided are immunostimulatory compositions, for instance for use in eliciting an immune response in a subject, such as an immune response to a latent tuberculosis infection. Kits for carrying out the provided methods are also described.


Find Patent Forward Citations

Loading…