The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 12, 2006

Filed:

Jun. 07, 1995
Applicants:

Wen-hwa Lee, San Antonio, TX (US);

H. Michael Shepard, Encinitas, CA (US);

Richard J. Gregory, Westford, MA (US);

Ken N. Wills, Encinitas, CA (US);

Daniel C. Maneval, San Diego, CA (US);

Eva Lee, San Antonio, TX (US);

David Goodrich, East Aurora, NY (US);

Nan-ping Wang, Bellevue, WA (US);

Inventors:

Wen-Hwa Lee, San Antonio, TX (US);

H. Michael Shepard, Encinitas, CA (US);

Richard J. Gregory, Westford, MA (US);

Ken N. Wills, Encinitas, CA (US);

Daniel C. Maneval, San Diego, CA (US);

Eva Lee, San Antonio, TX (US);

David Goodrich, East Aurora, NY (US);

Nan-Ping Wang, Bellevue, WA (US);

Assignees:

The Regents of the University of California, Oakland, CA (US);

Canji, Inc., Kenilworth, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/00 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Disclosed are methods of controlling cell cycle progression by introducing into a cell to be controlled a composition selected from the group consisting of p56protein, a fragment of the p56protein, and the gene encoding p56protein to alter the cell cycle progression while maintaining the viability of the cell. The p56protein has been found to have the unexpected and surprising characteristic of being soluble in low concentrations of glycerol, thereby enhancing its value in pharmaceutical applications and the gene encoding p56when delivered to the hyperproliferating cell inhibits cellular proliferation.


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