The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 05, 2006

Filed:

Dec. 09, 2004
Applicants:

Shankar Swaminathan, Monmouth Junction, NJ (US);

Ashvinikumar V. Gavai, Princeton Junction, NJ (US);

Junying Fan, Monmouth Junction, NJ (US);

Bharat P. Patel, Pennington, NJ (US);

Derek J. Norris, Pennington, NJ (US);

Richard Michael Corbett, Robbinsville, NJ (US);

Bin Zheng, Kendall Park, NJ (US);

Inventors:

Shankar Swaminathan, Monmouth Junction, NJ (US);

Ashvinikumar V. Gavai, Princeton Junction, NJ (US);

Junying Fan, Monmouth Junction, NJ (US);

Bharat P. Patel, Pennington, NJ (US);

Derek J. Norris, Pennington, NJ (US);

Richard Michael Corbett, Robbinsville, NJ (US);

Bin Zheng, Kendall Park, NJ (US);

Assignee:

Bristol-Myers Squibb Company, Princeton, NJ (US);

Attorney:
Int. Cl.
CPC ...
C07D 487/14 (2006.01); C07D 413/14 (2006.01); C07D 403/12 (2006.01); A61K 31/53 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides a process for preparing compounds of formula (I) or a pharmaceutically acceptable salt thereof. The compounds prepared by the process of the invention inhibit tyrosine kinase activity of growth factor receptors such as HER1, HER2 and HER4 thereby making them useful as antiproliferative agents for the treatment of cancer and other diseases.


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