The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 05, 2006
Filed:
Nov. 19, 2004
Ai Jeng Lin, North Potomac, MD (US);
Quan Zhang, Montgomery County, MD (US);
Jian Guan, Montgomery County, MD (US);
Wilbur K. Milhous, Germantown, MD (US);
Ai Jeng Lin, North Potomac, MD (US);
Quan Zhang, Montgomery County, MD (US);
Jian Guan, Montgomery County, MD (US);
Wilbur K. Milhous, Germantown, MD (US);
The United States of America as represented by the Secretary of the Army, Washington, DC (US);
Abstract
Disclosed herein are 2-guanidinylimidazolidinedione compounds having the structural formula A or B wherein Rand Rare each independently a hydrogen, halogen, alkyl, alkoxyl, amino, alkylamino or aralkyl, and wherein Ris an alkyl, cycloalkyl, heterocycloalkyl, acyl, aryl, heteroaryl, alkylaryl, sulfonyl, alkylsulfonyl, and pharmaceutically acceptable salts thereof, and methods of making thereof. Also disclosed are methods of treating, preventing, or inhibiting malaria with the 2-guanidinylimidazolidinedione compounds, and pharmaceutical compositions comprising the 2-guanidinylimidazolidinedione compounds, and kits.