The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 05, 2006

Filed:

Aug. 20, 1999
Applicants:

Mark Brian Anderson, Orinda, CA (US);

Haresh N. Vazir, San Diego, CA (US);

David Robert Luthin, Encinitas, CA (US);

Genevieve Deguzman Paderes, San Diego, CA (US);

Ved P. Pathak, San Diego, CA (US);

Lance Christopher Christie, Vista, CA (US);

Yufeng Hong, San Diego, CA (US);

Eileen Valenzuela Tompkins, Escondido, CA (US);

Haitao LI, San Diego, CA (US);

James Faust, San Diego, CA (US);

Inventors:

Mark Brian Anderson, Orinda, CA (US);

Haresh N. Vazir, San Diego, CA (US);

David Robert Luthin, Encinitas, CA (US);

Genevieve DeGuzman Paderes, San Diego, CA (US);

Ved P. Pathak, San Diego, CA (US);

Lance Christopher Christie, Vista, CA (US);

Yufeng Hong, San Diego, CA (US);

Eileen Valenzuela Tompkins, Escondido, CA (US);

Haitao Li, San Diego, CA (US);

James Faust, San Diego, CA (US);

Assignee:

Agouron Pharmaceuticals, Inc., San Diego, CA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 405/12 (2006.01); C07D 307/68 (2006.01); A61K 31/34 (2006.01); A61K 31/505 (2006.01); A61P 5/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Non-peptide GnRH agents capable of inhibiting the effect of gonadotropin-releasing hormone are described. Such compounds and their pharmaceutically acceptable salts, multimers, prodrugs, and active metabolites are suitable for treating mammalian reproductive disorders and steroid hormone-dependent tumors as well as for regulating fertility, where suppression of gonadotropin release is indicated. Methods for synthesizing the compounds and intermediates useful in their preparation are also described.


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