The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 05, 2006

Filed:

Nov. 20, 2001
Applicants:

Han Chang, Princeton Junction, NJ (US);

Wen-pin Yang, Princeton, NJ (US);

Yuli Wu, Newtown, PA (US);

Gena S. Whitney, Lawrenceville, NJ (US);

Juan J. Perez-villar, Mercerville, NJ (US);

Steven B. Kanner, Princeton, NJ (US);

Inventors:

Han Chang, Princeton Junction, NJ (US);

Wen-Pin Yang, Princeton, NJ (US);

Yuli Wu, Newtown, PA (US);

Gena S. Whitney, Lawrenceville, NJ (US);

Juan J. Perez-villar, Mercerville, NJ (US);

Steven B. Kanner, Princeton, NJ (US);

Assignee:

Bristol-Myers Squibb Company, Princeton, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P 21/06 (2006.01); C12N 15/63 (2006.01); C12N 15/00 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention describes a newly discovered full-length polynucleotide encoding an SH2/SH3 domain-containing adapter protein, called hSLAP-2, cloned, isolated and identified. Also described are the hSLAP-2 polypeptide sequence, expression vectors, host cells, agonists, antagonists, anti-sense molecules, and antibodies related to the polynucleotide and/or polypeptide of the present invention. Methods for screening for modulators, particularly inhibitors, of the hSLAP-2 protein and use of the hSLAP-2 polynucleotide and polypeptide for therapeutics and diagnostics are described.


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