The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 05, 2006
Filed:
Apr. 14, 2004
Thomas Jochen Schwalbe, Brookline, MA (US);
Volker Autze, Frankfurt am Main, DE;
Sebastian Oberbeck, Weilburg, DE;
Ansgar Kursawe, Frankfurt, DE;
Kemal Hünkar Sahin, Pittsburgh, PA (US);
Thomas Jochen Schwalbe, Brookline, MA (US);
Volker Autze, Frankfurt am Main, DE;
Sebastian Oberbeck, Weilburg, DE;
Ansgar Kursawe, Frankfurt, DE;
Kemal Hünkar Sahin, Pittsburgh, PA (US);
Cellular Process Chemistry, Inc., Cambridge, MA (US);
Abstract
A reaction system enables a plurality of optimization experiments for a reaction to be performed continuously, to enable optimal reaction parameters to be determined. Dilution pumps are included to automatically vary the solvent mixed with reactants so a concentration of each reactant can be selectively varied. The reactants are introduced into a reaction module selectively coupled to residence time chambers or directly to an analytical unit. The analytical unit determines the yield and/or quality for each optimization experiment, enabling optimal parameters to be determined. Residence time chambers can be employed sequentially to enable total residence time to be varied. The controller performs as many experiments as required to enable each parameter to be varied according to a predefined testing program and can redefine a testing program based on the results from previous experiments. At least two reaction parameters can be varied according to periodic functions to further enhance analytical efficiency.