The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 29, 2006
Filed:
Dec. 24, 1991
Applicants:
Magnus Pfahl, Solana Beach, CA (US);
Xiao-kun Zhang, La Jolla, CA (US);
Inventors:
Magnus Pfahl, Solana Beach, CA (US);
Xiao-kun Zhang, La Jolla, CA (US);
Assignee:
Ligand Pharmaceuticals, San Diego, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/435 (2006.01); G01N 33/78 (2006.01);
U.S. Cl.
CPC ...
Abstract
This invention provides a purified heterodimer comprising an RXR and a hormone receptor. The invention also provides a method of screening ligands for their effect on the activity of an RXR-containing hormone receptor heterodimer comprising combining the heterodimer with the ligand and determining the effect on activity. Also provided is a method of amplifying the activity of a hormone receptor comprising forming a heterodimer with another hormone receptor.