The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 29, 2006
Filed:
Dec. 10, 2003
Georg Fertig, Penzberg, DE;
Frank Herting, Penzberg, DE;
Matthias Koerner, Antdorf, DE;
Manfred Kubbies, Penzberg, DE;
Anja Limberg, Munich, DE;
Ulrike Reiff, Penzberg, DE;
Michael Weidner, Penzberg, DE;
Georg Fertig, Penzberg, DE;
Frank Herting, Penzberg, DE;
Matthias Koerner, Antdorf, DE;
Manfred Kubbies, Penzberg, DE;
Anja Limberg, Munich, DE;
Ulrike Reiff, Penzberg, DE;
Michael Weidner, Penzberg, DE;
Hoffmann-La Roche Inc., Nutley, NJ (US);
Abstract
The present invention describes compounds of the general formula I as well as processes for their manufacture, pharmaceutical compositions containing them and methods for using these compounds and pharmaceutical compositions as pharmaceutical agents. The compounds according to this invention show antiproliferative and differentiation-inducing activity, which results in inhibition of tumor cell proliferation, induction of apoptosis and inhibition of invasion.