The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 29, 2006
Filed:
Aug. 28, 2003
Koji Nagai, Itabashi-ku, JP;
Masatoshi Taniguchi, Tsukuba, JP;
Nobuaki Shindo, Tsukuba, JP;
Yoh Terada, Tsukuba, JP;
Masamichi Mori, Tsukuba, JP;
Nobuaki Amino, Tsukuba, JP;
Ken-ichi Suzumura, Tsukuba, JP;
Isao Takahashi, Itabashi-ku, JP;
Mitsuo Amase, Itabashi-ku, JP;
Koji Nagai, Itabashi-ku, JP;
Masatoshi Taniguchi, Tsukuba, JP;
Nobuaki Shindo, Tsukuba, JP;
Yoh Terada, Tsukuba, JP;
Masamichi Mori, Tsukuba, JP;
Nobuaki Amino, Tsukuba, JP;
Ken-ichi Suzumura, Tsukuba, JP;
Isao Takahashi, Itabashi-ku, JP;
Mitsuo Amase, Itabashi-ku, JP;
Astellas Pharma INC, Tokyo, JP;
Abstract
The present invention relates to a novel compound which is useful as an agent for prevention and treatment of diseases associated with HDAC, in particular, tumor or cell proliferative diseases. The depsipeptide compound or its pharmaceutically acceptable salt of the present invention has a good HDAC inhibitory activity and an inhibitory activity of cell proliferation against human cancer cells and, therefore, is useful in treatment and improvement of diseases and pathogenic conditions associated with histone acetylation, in particular, tumor or cell proliferative diseases.