The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 29, 2006
Filed:
Sep. 13, 2002
Andre Choulika, Paris, FR;
Jean-stephane Joly, Versailles, FR;
Violette Thermes, Paris, FR;
Filomena Ristoratore, Ercolano, IT;
Andre Choulika, Paris, FR;
Jean-Stephane Joly, Versailles, FR;
Violette Thermes, Paris, FR;
Filomena Ristoratore, Ercolano, IT;
Cellectis SA, Paris, FR;
Abstract
The present invention concerns a method for in vivo generation of a linear polynucleotide with 5' and 3′ free ends from a vector having no free end, said linear polynucleotide being integrated into the host cell genome. The vector having no free end according to the present invention comprise the polynucleotide to be linearized or excised flanked by a cleavage site, said cleavage site being preferably not found in the host cell genome. The present invention also relates to the resulting cells and their uses, for example for production of proteins or other genes, biomolecules, biomaterials, transgenic plants, vaccines, transgenic animals or for treatment or prophylaxis of a condition or disorder in an individual.