The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 29, 2006
Filed:
Jul. 31, 2002
David B Seifer, Holmdel, NJ (US);
Robert Shelden, Kendall Park, NJ (US);
BO Feng, Edison, NJ (US);
Cheryl Dreyfus, Short Hills, NJ (US);
David B Seifer, Holmdel, NJ (US);
Robert Shelden, Kendall Park, NJ (US);
Bo Feng, Edison, NJ (US);
Cheryl Dreyfus, Short Hills, NJ (US);
University of Medicine and Dentistry of New Jersey, New Brunswick, NJ (US);
Abstract
Methods and kits are provided for manipulating and predicting the reproductive capacity of a female subject. The presence of endogenous neurotrophins and addition of exogenous neurotrophins, particularly BDNF, NT-4/5, and NGF, increase the reproductive capacity of a female patient by binding to receptors on the oocytes and stimulating maturation of the oocytes. Administration of antagonists act as a contraceptive because the antagonists prevent the neurotrophins from binding to oocyte receptors. Neurotrophins may also be used to stimulate the maturation of oocyte in vitro.