The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 29, 2006

Filed:

May. 27, 2003
Applicants:

Kurt Klimpel, San Diego, CA (US);

Theresa J. Goletz, Kensington, MD (US);

Naveen Arora, Delhi, IN;

Stephen H. Leppla, Bethesda, MD (US);

Jay A. Berzofsky, Bethesda, MD (US);

Inventors:

Kurt Klimpel, San Diego, CA (US);

Theresa J. Goletz, Kensington, MD (US);

Naveen Arora, Delhi, IN;

Stephen H. Leppla, Bethesda, MD (US);

Jay A. Berzofsky, Bethesda, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); C07K 19/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides a vaccine for inducing an immune response in mammal to a specific antigen, where the vaccine comprises a unit dose of a binary toxin protective antigen and the antigen, which is bound to a binary toxin protective antigen binding protein. In one embodiment the vaccine is comprised of an anthrax protective antigen and the antigen bound to anthrax protective antigen binding protein. The present invention also provides a method of immunizing a mammal against an antigen using the vaccine, and a method of inducing antigen-presenting mammalian cells to present specific antigens via the MHC class I processing pathway.


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