The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 22, 2006

Filed:

Oct. 31, 2002
Applicants:

Markus Albers, Leverkusen, DE;

Klaus Urbahns, Wuppertal, DE;

Andrea Vaupel, Wuppertal, DE;

Michael Härter, Leverkusen, DE;

Delf Schmidt, Wuppertal, DE;

Beatrix Stelte-ludwig, Wulfrath, DE;

Christoph Gerdes, Leverkusen, DE;

Elke Stahl, Bergisch Gladbach, DE;

Jörg Keldenich, Wuppertal, DE;

Ulf Brueggemeier, Leverkusen, DE;

Klemens Lustig, Wuppertal, DE;

Inventors:

Markus Albers, Leverkusen, DE;

Klaus Urbahns, Wuppertal, DE;

Andrea Vaupel, Wuppertal, DE;

Michael Härter, Leverkusen, DE;

Delf Schmidt, Wuppertal, DE;

Beatrix Stelte-Ludwig, Wulfrath, DE;

Christoph Gerdes, Leverkusen, DE;

Elke Stahl, Bergisch Gladbach, DE;

Jörg Keldenich, Wuppertal, DE;

Ulf Brueggemeier, Leverkusen, DE;

Klemens Lustig, Wuppertal, DE;

Assignee:

Bayer Aktiengesellschaft, Leverkusen, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 333/24 (2006.01); C07D 333/36 (2006.01); C07D 409/06 (2006.01); A61K 31/38 (2006.01); A61P 19/10 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to biphenyl and biphenyl-analogous compounds, their preparation and use as pharmaceutical compositions, as integrin antagonists and in particular for the production of pharmaceutical compositions for the treatment and prophylaxis of cancer, arteriosclerosis, restenosis, osteolytic disorders such as osteoporosis and ophthalmic diseases. The compounds according to the invention have the formula (1) wherein


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