The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 22, 2006
Filed:
Aug. 09, 2001
Applicants:
Stefan Lehmann, Ober-Klingen, DE;
Thomas Koppe, Schaffhausen, CH;
Inventors:
Stefan Lehmann, Ober-Klingen, DE;
Thomas Koppe, Schaffhausen, CH;
Assignee:
Merck Patent GmbH, Darmstadt, DE;
Primary Examiner:
Int. Cl.
CPC ...
C07D 235/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention relates to a gentle process for catalytic hydrogenation and to a process for the preparation of biotin using the hydrogenation step. The process according to the invention for the selective, catalytic hydrogenation of a C—C double bond on a thiazole ring system having at least one functional group which can be converted into a salt under basic conditions is characterised in that the hydrogenation is carried out in a protic solvent is a pH>7.