The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 22, 2006

Filed:

Oct. 07, 2004
Applicants:

M. V. Ramana Reddy, Upper Darby, PA (US);

Stanley C. Bell, Narberth, PA (US);

Inventors:

M. V. Ramana Reddy, Upper Darby, PA (US);

Stanley C. Bell, Narberth, PA (US);

Assignee:

Onconova Therapeutics, Inc., Lawrenceville, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 261/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Provided are compounds, processes and synthetic intermediates useful for the preparation of compounds of the formula I and IX wherein Ris selected from the group consisting of hydrogen, trihalomethyl, C–Calkyl and substituted or unsubstituted phenyl; Y is a group of the formula wherein Ris selected from the group consisting of C–Calkyl, C–Calkanoylamino and amino; and Ris selected from the group consisting of hydrogen, amino, halogen, hydroxyl, nitro, C–Calkyl, C–Calkoxy, carboxy, C–Ctrihaloalkyl, cyano, phosphonato, and hydroxyalkyl; and Z is selected from the group consisting of substituted and unsubstituted aryl. Also provided are certain N-acylated analogs of compounds of the formula I and IX, and processes for their preparation.


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