The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 22, 2006
Filed:
Feb. 19, 2004
Applicant:
Foe S. Tjoeng, Ballwin, MO (US);
Inventor:
Foe S. Tjoeng, Ballwin, MO (US);
Assignee:
Pharmacia Corporation, Chesterfield, MO (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 207/404 (2006.01); C07D 249/18 (2006.01); C07K 1/113 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention relates to the preparation of polyethylene glycol carbonate active esters useful for the PEGylation of biological active and pharmaceutically useful peptides and proteins. The invention involves the use of activated carbonate and oxalate esters in the formation of polyethylene glycol mixed carbonate active esters that then react with a linker or directly with a target peptide or protein.