The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 22, 2006

Filed:

Jul. 31, 2003
Applicants:

Wieslaw M. Cholody, Frederick, MD (US);

Valentina Petukhova, Rockville, MD (US);

Sean O'brien, Gaithersburg, MD (US);

Norman Ohler, New Market, MD (US);

Stanislaw Pikul, Germantown, MD (US);

Inventors:

Wieslaw M. Cholody, Frederick, MD (US);

Valentina Petukhova, Rockville, MD (US);

Sean O'Brien, Gaithersburg, MD (US);

Norman Ohler, New Market, MD (US);

Stanislaw Pikul, Germantown, MD (US);

Assignee:

Avalon Pharmaceuticals, Inc., Germantown, MD (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/445 (2006.01); C07D 207/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Chemical agents of the general formula (I) and (II), such as derivatives of 3-hydroxy-pyrrole containing hydroxamic acid, and including salts thereof, that modulate levels of gene expression in cellular systems, including cancer cells, are disclosed, along with methods for preparing such agents, as well as pharmaceutical compositions containing such agents as active ingredients and methods of using these as therapeutic agents.


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